166 research outputs found

    Testing demand responsive shared transport services via agent-based simulations

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    Demand Responsive Shared Transport DRST services take advantage of Information and Communication Technologies ICT, to provide on demand transport services booking in real time a ride on a shared vehicle. In this paper, an agent-based model ABM is presented to test different the feasibility of different service configurations in a real context. First results show the impact of route choice strategy on the system performance

    Intrauterine versus post-mortem magnetic resonance in second trimester termination of pregnancy for central nervous system abnormalities

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    Objective: To evaluate if limiting factors of intrauterine magnetic resonance imaging (iuMRI) performed in the early second trimester of pregnancy (19\u201323 weeks) affect its accuracy in comparison to post-mortem MRI (pmMRI) in fetuses that underwent termination of pregnancy (TOP) for central nervous system (CNS) defects. Study design: This is a secondary analysis of a 10 years prospective observational study. Cases of TOP < 23 weeks for CNS malformation that had undergone neurosonography (NSG), iuMRI, pmMRI and autopsy were included. The agreement between iuMRI and pmMRI was calculated. The autopsy represented the gold-standard. Results: Overall, 143 TOPs for fetal congenital anomaly underwent the post-mortem diagnostic protocol. Of these, 31 cases underwent iuMRI and pmMRI for CNS abnormality. Three cases were excluded due to brain autolysis at autopsy. Corpus callosum defects were the most represented (16/28; 57 %). In only one case of posterior fossa defect, pmMRI identified the presence of vermian hypoplasia not diagnosed at iuMRI. In 2 cases (7%), iuMRI added clinically relevant additional findings to NSG, that were posteriorly confirmed by pmMRI. Conclusions: The study shows that, at 19\u201323 weeks and for CNS defects, limiting factors that might influence the performance of iuMRI have little influence on iuMRI accuracy. This finding is particularly important for professionals who work in countries with legal bound for TOP in the early second trimester

    Formation of stable DNA triple helices within the human bcr promoter at a critical oligopurine target interrupted in the middle by two adjacent pyrimidines

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    A kinetic study of triple-helix formation at a critical R-Y sequence of the murine c-Ki-ras promoter by (A,G)- and (G,T)oligonucleotides

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    Analisi comparativa dei consumi energetici e delle emissioni inquinanti di tipologie alternative di trasporto pubblico su strada

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    Il capitolo discute le prestazioni ambientali dei servizi di trasporto pubblico innovativi. Vengono presentate diverse tipologie di servizio, paragonate tra loro e calcolati i consumi e le emissioni inquinant

    Emissions of demand responsive services as an alternative to conventional transit systems

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    The environmental performance of public transport plays a key role in improving air quality in urban areas. An important way of improving existing transit services is to use innovative propulsive systems; however, this needs considerable financial resources that are not always available. Here we assess how the organizational form of the transit system may impact the environment relying on a new methodology that permits comparisons in terms of distance traveled between a traditional fixed-route and a demand responsive transit service. We apply an emission model to find the least polluting transit system under a broad range of scenarios with different road networks, service quality levels and demand densities. Results indicate that demand responsive transit services minimize emissions for high quality service level and low demand density scenarios. Furthermore, the possibility of employing smaller vans with lower emission factors guarantees additional substantial benefits in terms of atmospheric pollution for demand responsive transit services, thereby giving them a competitive advantage in virtually every case

    A methodology for comparing distances traveled by performance-equivalent fixed-route and demand responsive transit services

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    Public transport systems are confronted by the need to improve their economic effectiveness in order to meet customer requirements at acceptable costs for transit providers, which are often heavily subsidized. Our goal is to understand how the organizational form of the transit system impacts on system productivity. Our methodology consists of comparing performance in terms of distance traveled of two competing transit services, a traditional fixed-route and a demand responsive service, while ensuring a comparable service to the same set of customers. We consider several scenarios, which depend on the road network, service quality level, and demand density. According to our findings, demand responsive transit services perform better for highquality service levels and low demand density scenarios
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